Southern Sisters Boutique will open at 115 E. Poinsett Street in late September.
Danielle and Mary Prestifilippo specialize in jewelry and accessories.
Danielle has her own line, Bella Daniella Jewelry, featuring mosaic pendants, pressed flower, retro women necklaces, belt buckles and deco mesh wreaths.
The boutique will locate in the vacancy created by ZuZu’s Fashion Replay.
Danielle is returning south after moving to Edmonton, Alberta two years ago from Augusta, Ga. She studied biology and graduated Georgia Southern University.
The tentative opening is scheduled Friday, Sept. 26.